JUVÉDERM®is a smooth consistency gel made of hyaluronic acid—a naturally occurring substance in your skin, that helps to add volume and hydration. Juvéderm is eased under the skin using a fine needle to augment, or fill, the soft tissue of the dermis, the dense inner layer of skin beneath the epidermis, to add volume and diminish wrinkles and folds. JUVÉDERM® injectable gel is used most effectively for those wrinkles and folds in the lower third of your face, like your laugh lines, smile lines or the lines on the sides of your nose and mouth, known as the nasolabial folds. JUVÉDERM®, like Restylane, is made from hyaluronic acid, a naturally occurring substance in your skin that helps to hydrate and add volume. Hyaluronic acid may diminish with age, contributing to the formation of wrinkles and folds. JUVÉDERM® injectable gel works to correct this by restoring hyaluronic acid in your skin, helping to smooth wrinkles and folds.